Osamu Sakamoto Selected Research

Isovaleryl-CoA Dehydrogenase (Isovaleryl-Coenzyme A Dehydrogenase)

6/2017	Isovaleric acidemia: Therapeutic response to supplementation with glycine, l-carnitine, or both in combination and a 10-year follow-up case study.
12/2011	Phenotypic and mutation spectrums of Thai patients with isovaleric acidemia.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Osamu Sakamoto Research Topics

Disease

5	Adult-onset citrullinemia type 2 01/2021 - 05/2003
4	Citrullinemia 01/2019 - 05/2003
4	Neonatal-onset citrullinemia type 2 01/2019 - 05/2003
4	Propionic Acidemia 01/2017 - 04/2004
4	Fanconi Syndrome (Syndrome, Fanconi) 08/2012 - 03/2009
3	Disease Progression 06/2017 - 12/2003
3	isovaleric Acidemia 06/2017 - 12/2011
3	Methylmalonic acidemia 09/2013 - 08/2004
3	Interstitial Lung Diseases (Interstitial Lung Disease) 07/2013 - 07/2008
2	Hypoglycemia (Reactive Hypoglycemia) 01/2020 - 08/2012
2	Cholestasis 01/2019 - 03/2005
2	Galactosemias (Galactosemia) 01/2019 - 01/2019
2	Hypophosphatemic Rickets 08/2012 - 03/2009
2	Hepatomegaly 08/2012 - 03/2009
2	Infections 01/2010 - 02/2002
2	Intrahepatic Cholestasis 11/2004 - 05/2003
1	Jaundice (Icterus) 01/2021
1	Liver Failure 01/2019
1	Maternal Phenylketonuria 10/2018
1	Atrophy 06/2017
1	Pancreatitis 01/2017
1	Bacteremia 01/2017
1	Sepsis (Septicemia) 01/2017
1	Zellweger Syndrome (Zellweger's Syndrome) 12/2015
1	Lung Neoplasms (Lung Cancer) 08/2015
1	Pneumonia (Pneumonitis) 08/2015
1	Neoplasms (Cancer) 08/2015
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2015
1	Adenocarcinoma 08/2015
1	Intellectual Disability (Idiocy) 04/2015
1	Seizures (Absence Seizure) 04/2015
1	B BH4-Deficient Hyperphenylalaninemia 03/2014
1	Brain Diseases (Brain Disorder) 01/2014
1	Infantile Spasms (West Syndrome) 01/2014
1	Methylmalonic aciduria cblA type 09/2012
1	Failure to Thrive 08/2012
1	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 03/2012
1	Inflammation (Inflammations) 03/2012
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2012
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2012
1	Lactose Intolerance (Intolerance, Lactose) 01/2012
1	Congenital Lactase Deficiency 01/2012

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2003
5	Galactose (Galactopyranose)FDA LinkGeneric 01/2019 - 05/2003
4	EnzymesIBA 01/2019 - 08/2004
4	citrinIBA 01/2019 - 05/2003
4	AcidsIBA 06/2017 - 04/2004
3	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 10/2011
3	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 09/2013 - 08/2004
3	GlycogenIBA 08/2012 - 03/2009
3	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 08/2012 - 03/2009
3	DNA (Deoxyribonucleic Acid)IBA 04/2012 - 05/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2008 - 02/2002
2	VitaminsIBA 01/2019 - 08/2004
2	Lactose FDA LinkGeneric 01/2019 - 01/2012
2	sapropterin (tetrahydrobiopterin)FDA Link 10/2018 - 03/2014
2	Isovaleryl-CoA Dehydrogenase (Isovaleryl-Coenzyme A Dehydrogenase)IBA 06/2017 - 12/2011
2	Carnitine (L-Carnitine)FDA LinkGeneric 06/2017 - 06/2017
2	6-propylchromone-2-carboxylic acid (PCCA)IBA 07/2016 - 04/2004
2	Propionyl-Coenzyme A Carboxylase (Propionyl CoA Carboxylase)IBA 02/2014 - 04/2004
2	Methylmalonyl-CoA MutaseIBA 01/2007 - 08/2004
2	Bile Acids and Salts (Bile Acids)IBA 03/2005 - 11/2004
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021
1	KetonesIBA 01/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Ketone BodiesIBA 01/2020
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2019
1	LipidsIBA 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	Vitamin K 2 (Vitamin K2)IBA 01/2019
1	glutarylcarnitineIBA 06/2017
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 06/2017
1	alpha-glycerophosphoric acid (sodium glycerophosphate)IBA 09/2015
1	aspartate-glutamate carrierIBA 09/2015
1	Glycerol (Glycerine)FDA LinkGeneric 09/2015
1	Glycerolphosphate Dehydrogenase (Glycerol 3 Phosphate Dehydrogenase)IBA 09/2015
1	Protein Isoforms (Isoforms)IBA 09/2015
1	ErbB Receptors (EGF Receptor)IBA 08/2015
1	Alkaline PhosphataseIBA 04/2015
1	Leucine (L-Leucine)FDA Link 01/2015
1	Guanosine Triphosphate (GTP)IBA 03/2014
1	Serotonin (5 Hydroxytryptamine)IBA 03/2014
1	Dopamine (Intropin)FDA LinkGeneric 03/2014
1	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2014
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2014
1	Glutamine (L-Glutamine)FDA Link 01/2014
1	Glutamic Acid (Glutamate)FDA Link 01/2014
1	Surface-Active Agents (Surfactants)IBA 07/2013
1	Protein CIBA 07/2013
1	GadoliniumIBA 03/2012

Therapy/Procedure

6	Therapeutics 01/2014 - 06/2005
2	Renal Dialysis (Hemodialysis) 01/2017 - 01/2012
1	Intravenous Administration 01/2020
1	Liver Transplantation 01/2019
1	Diet Therapy (Therapy, Diet) 06/2017
1	Central Venous Catheters 01/2017
1	Catheters 01/2017
1	Total Parenteral Nutrition 01/2017
1	Aftercare (After-Treatment) 08/2015
1	Transplantation 03/2012